They can't play every match if we qualify for group stages in the EL. With cup games we are looking well above 50 games for this season. 38 league matches, 2 EL qualifying matches, 2 EL knockout matches, 8 EL group matches, 1 League Cup and 1 FA Cup is the minimum in that case. I would hope there'd be at least another 5 or so games on top of that (or we have a crap cup year) so it could be closer to sixty games - and with good cup runs it could go above that.
What if we go far in the EL and are still in the hunt for a top four spot come April? On top of league matches there could be four EL matches (quarter and semi-finals).